Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases
نویسندگان
چکیده
منابع مشابه
Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)
Colitis can occur from viral or bacterial infections, ischemic insult, or autoimmune disorders; most notably Ulcerative Colitis and the colonic variant of Crohn's Disease - Crohn's Colitis. Acute colitis may present with abdominal pain and distention, malabsorption, diarrhea, hematochezia and mucus in the stool. We are beginning to understand the complex interactions between the environment, ge...
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Changes in the composition of intestinal fungi and their role in mice with dextran sulfate sodium-induced colitis
Intestinal fungi are increasingly believed to greatly influence gut health. However, the effects of fungi on intestinal inflammation and on gut bacterial constitution are not clear. Here, based on pyrosequencing method, we reveal that fungal compositions vary in different intestinal segments (ileum, cecum, and colon), prefer different colonization locations (mucosa and feces), and are remarkabl...
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ژورنال
عنوان ژورنال: BMC Immunology
سال: 2012
ISSN: 1471-2172
DOI: 10.1186/1471-2172-13-41